The ultimate spiritual teaching seems to focus on Nothingness. That nothing we see around us is real. Nothing is truly relevant, because in the long run, we are all reduced to nothing. The 3 gunas sattva rajas and tamas are great, but if you want to attain God you have to go beyond, to nothing. Ego is the root cause of all problems, so give up ego, and become one with nothing.
But is this practical? Not for me at least, nope. The flip side to nothing is everything. Instead of constantly being focused only on ourselves, we can focus on others around us, which will automatically drive down the ego. The Lord might be in nothing, but He sure is in everything as well. Gratitude for everything we have in life is much easier than gratitude in nothing. While creation might seem unreal in a spirituality textbook, everything is real enough to us inside this body.
So its perhaps not Nothingness, but Everythingness that is an easier answer.